Odom Laboratory

Dr. Guy Odom is a Research Associate Professor in the Department of Neurology at the University of Washington; whose research focuses on neuromuscular disease with an emphasis on the muscular dystrophies (MD’s).  As an example, gene mutations that affect production of the protein dystrophin are the cause of Duchenne muscular dystrophy (DMD) the most common lethally inherited disorder of children.  A primary research interest in the Odom lab is to develop a more thorough understanding of the inherent muscle biology occurring during MD disease progression.  Additionally, to identify contributory protein-protein interactions, biomarkers, & the like as potential therapeutic targets. As such, the labs’ research generally involves developing or improving genetic-based therapies. To that end, approaches often utilized include viral vector technology, high-resolution microscopy, omics technologies, incorporation of machine learning-based modeling, applying non-invasive imaging techniques & evaluating striated muscle contractile performance in dystrophic animal models.