April 28, 2022
Congratulations to Dr. Chris Ransom for his VA Clinician Scientist Investigator Award
VA BLR&D Program Officials can nominate one fundable grant from their panels each cycle. Dr. Chris Ransom was nominated and received the Award for his research:
“Regulation of extrasynaptic GABA-A receptors in health and disease”
This project will study cellular and molecular changes that occur after experiment TBI, with focus on extrasynaptic GABA receptors (both GABA-A and GABA-B receptors) in areas of the brain that are not directly involved in cortical impact (i.e. hippocampus and thalamus). It will also assess the microglia-dependence of TBI-related cellular/molecular changes and functional outcomes (e.g. epileptic seizures) using approaches to deplete microglia or limit microglia responses to injury.